Found 9 matching trials
NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast Cancer PHASE2 This randomized, parallel cohort, two stage, double-blind, placebo-controll...
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Novartis Investigative Site
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A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab PHASE1 The purpose of the trial is to determine the maximum tolerated dose (MTD) o...
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Novartis Investigative Site
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Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer PHASE2 This phase II trial studies the effects of paclitaxel combined with phospho...
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Multiple Locations
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Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy PHASE2 Phase II Study of efficacy and safety of buparlisib (BKM120) plus paclitaxe...
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Highlands Oncology Group
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Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian Cancer PHASE1 The purpose of the first part of this study or the dose escalation portion ...
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Multiple Locations
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BKM120 + Carboplatin + Paclitaxel for Patients With Advanced Solid Tumors PHASE1 The purpose of this study is to find out the good and bad effects that occu...
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Memorial Sloan Kettering Cancer Center
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A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation PHASE2 This study evaluated whether the addition of daily BKM120 to weekly paclita...
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Ironwood Cancer and Research Centers SC
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The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC PHASE3 The BURAN study is a randomized, open-label phase III study to assess the t...
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Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer PHASE1 The Phase Ib part of the study aimed to determine the maximum tolerated dos...
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Highlands Oncology Group
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